Pharmacometabolomics Reveals a Role for Histidine, Phenylalanine and Threonine in the Development of Paclitaxel-induced Peripheral Neuropathy

PURPOSE: Approximately 25% of breast cancer patients experience treatment delays or discontinuation due to paclitaxel-induced peripheral neuropathy (PN). Currently, there are no predictive biomarkers of PN. Pharmacometabolomics is an informative tool for biomarker discovery of drug toxicity. We cond...

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Publicado no:Breast Cancer Res Treat
Main Authors: Sun, Yihan, Kim, Jae Hyun, Vangipuram, Kiran, Hayes, Daniel F, Lavoie Smith, Ellen M., Yeomans, Larisa, Henry, N Lynn, Stringer, Kathleen A., Hertz, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119501/
https://ncbi.nlm.nih.gov/pubmed/29946863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-018-4862-3
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