The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins

We have shown that a lentiviral vector (rSIV.F/HN) pseudotyped with the F and HN proteins from Sendai virus generates high levels of intracellular proteins after lung transduction. Here, we evaluate the use of rSIV.F/HN for production of secreted proteins. We assessed whether rSIV.F/HN transduction...

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Detalhes bibliográficos
Publicado no:Gene Ther
Main Authors: Paul-Smith, Michael C., Pytel, Kamila M., Gelinas, Jean-François, McIntosh, Jenny, Pringle, Ian, Davies, Lee, Chan, Mario, Meng, Cuixiang, Bell, Robyn, Cammack, Lidia, Moran, Caroline, Cameron, Loren, Inoue, Makoto, Tsugumine, Shu, Hironaka, Takashi, Gill, Deborah R., Hyde, Stephen C., Nathwani, Amit, Alton, Eric W. F. W., Griesenbach, Uta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119181/
https://ncbi.nlm.nih.gov/pubmed/30022127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41434-018-0025-8
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