Nalaganje...
Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk
Coding variants represent many of the strongest associations between genotype and phenotype, however they exhibit inter-individual differences in effect, termed variable penetrance. Here, we study how cis-regulatory variation modifies the penetrance of coding variants. Using functional genomic and g...
Shranjeno v:
| izdano v: | Nat Genet |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6119105/ https://ncbi.nlm.nih.gov/pubmed/30127527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0192-y |
| Oznake: |
Označite
Brez oznak, prvi označite!
|