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Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells
Myeloid-derived suppressor cells (MDSCs) densely accumulate into tumors and potently suppress antitumor immune responses, promoting tumor development. Targeting MDSCs in tumor immunotherapy has been hampered by lack of understanding of the molecular pathways that govern MDSC differentiation and func...
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| 出版年: | J Clin Invest |
|---|---|
| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6118632/ https://ncbi.nlm.nih.gov/pubmed/29920188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120888 |
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