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In Vivo Ablation of Plasmacytoid Dendritic Cells Inhibits Autoimmunity through Expansion of Myeloid-Derived Suppressor Cells

Autoimmunity ensues upon breakdown of tolerance mechanism and priming of self-reactive T cells. Plasmacytoid dendritic cells (pDCs) constitute a unique cell subset that participates in the activation of autoreactive T cells but also has been shown to be critically involved in the induction of self-t...

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Detalhes bibliográficos
Main Authors: Ioannou, Marianna, Alissafi, Themis, Boon, Louis, Boumpas, Dimitrios, Verginis, Panayotis
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586977/
https://ncbi.nlm.nih.gov/pubmed/23382560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201897
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