Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis

Red blood cells (RBCs) influence rheology, and release ADP, ATP, and nitric oxide, suggesting a role for RBCs in hemostasis and thrombosis. Here, we provide evidence for a significant contribution of RBCs to thrombus formation. Anemic mice showed enhanced occlusion times upon injury of the carotid a...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Klatt, Christoph, Krüger, Irena, Zey, Saskia, Krott, Kim-Jürgen, Spelleken, Martina, Gowert, Nina Sarah, Oberhuber, Alexander, Pfaff, Lena, Lückstädt, Wiebke, Jurk, Kerstin, Schaller, Martin, Al-Hasani, Hadi, Schrader, Jürgen, Massberg, Steffen, Stark, Konstantin, Schelzig, Hubert, Kelm, Malte, Elvers, Margitta
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118585/
https://ncbi.nlm.nih.gov/pubmed/29952767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI92077
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