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Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling

Bile acids are critical biological detergents in the gastrointestinal tract and also act as messengers to regulate a multitude of intracellular signaling events, including mitogenic signaling, lipid metabolism and endo/exocytosis. In particular, bile acids stimulate many receptors and ion channels o...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Liang, Hong, Estes, Mary K., Zhang, Huiling, Du, Guangwei, Zhou, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118352/
https://ncbi.nlm.nih.gov/pubmed/30169511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0198983
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