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Acute Effects of Drugs on Caenorhabditis elegans Movement Reveal Complex Responses and Plasticity

Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of drugs on C. elegans movement and examined the effect...

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Dades bibliogràfiques
Publicat a:G3 (Bethesda)
Autors principals: Spensley, Mark, Del Borrello, Samantha, Pajkic, Djina, Fraser, Andrew G.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118317/
https://ncbi.nlm.nih.gov/pubmed/30061375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200374
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