Inhaled sGC Modulator Can Lower PH in Patients With COPD Without Deteriorating Oxygenation

This study uses a highly fidelity computational simulator of pulmonary physiology to evaluate the impact of a soluble guanylate cyclase (sGC) modulator on gas exchange in patients with chronic obstructive pulmonary disease (COPD) and pulmonary hypertension (PH) as a complication. Three virtual patie...

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Dettagli Bibliografici
Pubblicato in:CPT Pharmacometrics Syst Pharmacol
Autori principali: Saffaran, Sina, Wang, Wenfei, Das, Anup, Schmitt, Walter, Becker‐Pelster, Eva‐Maria, Hardman, Jonathan G., Weimann, Gerrit, Bates, Declan G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118299/
https://ncbi.nlm.nih.gov/pubmed/29962065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12308
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