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The Lung Microbiota of Healthy Mice Are Highly Variable, Cluster by Environment, and Reflect Variation in Baseline Lung Innate Immunity

Rationale: The “gut–lung axis” is commonly invoked to explain the microbiome’s influence on lung inflammation. Yet the lungs harbor their own microbiome, which is altered in respiratory disease. The relative influence of gut and lung bacteria on lung inflammation is unknown. Objectives: To determine...

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Опубликовано в: :Am J Respir Crit Care Med
Главные авторы: Dickson, Robert P., Erb-Downward, John R., Falkowski, Nicole R., Hunter, Ellen M., Ashley, Shanna L., Huffnagle, Gary B.
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118022/
https://ncbi.nlm.nih.gov/pubmed/29533677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201711-2180OC
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