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Lung and gut microbiota are altered by hyperoxia and contribute to oxygen-induced lung injury in mice

Inhaled oxygen, although commonly administered to patients with respiratory disease, causes severe lung injury in animals and is associated with poor clinical outcomes in humans. The relationship between hyperoxia, lung and gut microbiota, and lung injury is unknown. Here, we show that hyperoxia con...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Ashley, Shanna L., Sjoding, Michael W., Popova, Antonia P., Cui, Tracy X., Hoostal, Matthew J., Schmidt, Thomas M., Branton, William R., Dieterle, Michael G., Falkowski, Nicole R., Baker, Jennifer M., Hinkle, Kevin J., Konopka, Kristine E., Erb-Downward, John R., Huffnagle, Gary B., Dickson, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732030/
https://ncbi.nlm.nih.gov/pubmed/32801143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aau9959
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