ERS Special Article. Reversing Mechanoinductive DSP Expression by CRISPR/dCas9–mediated Epigenome Editing

Rationale: DSP (desmoplakin), the most abundant component of desmosomes, which maintain the mechanical integrity of epithelium, is a genome-wide association study–identified genetic risk locus in human idiopathic pulmonary fibrosis (IPF). Subjects with IPF express a significantly higher level of DSP...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Am J Respir Crit Care Med
Main Authors: Qu, Jing, Zhu, Lanyan, Zhou, Zijing, Chen, Ping, Liu, Shuyan, Locy, Morgan L., Thannickal, Victor J., Zhou, Yong
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118013/
https://ncbi.nlm.nih.gov/pubmed/29924937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201711-2242OC
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker