A structurally derived model of subunit‐dependent NMDA receptor function

KEY POINTS: The kinetics of NMDA receptor (NMDAR) signalling are a critical aspect of the physiology of excitatory synaptic transmission in the brain. Here we develop a mechanistic description of NMDAR function based on the receptor tetrameric structure and the principle that each agonist‐bound subu...

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Detalles Bibliográficos
Publicado en:J Physiol
Main Authors: Gibb, Alasdair J., Ogden, Kevin K., McDaniel, Miranda J., Vance, Katie M., Kell, Steven A., Butch, Chris, Burger, Pieter, Liotta, Dennis C., Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Molecular and Cellular
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117563/
https://ncbi.nlm.nih.gov/pubmed/29917241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276093
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