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The PHD1 oxygen sensor in health and disease
The hypoxia‐inducible factor (HIF) co‐ordinates the adaptive transcriptional response to hypoxia in metazoan cells. The hypoxic sensitivity of HIF is conferred by a family of oxygen‐sensing enzymes termed HIF hydroxylases. This family consists of three prolyl hydroxylases (PHD1–3) and a single aspar...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Physiol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6117546/ https://ncbi.nlm.nih.gov/pubmed/29435987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275327 |
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