The interplay between microbes and the immune response in inflammatory bowel disease

The aetiology and pathogenesis of inflammatory bowel disease (IBD) remains unclear but involves a complex interplay between genetic risk, environmental exposures, the immune system and the gut microbiota. Nearly two decades ago, the first susceptibility gene for Crohn's disease, NOD2, was ident...

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Veröffentlicht in:J Physiol
Hauptverfasser: Goethel, Ashleigh, Croitoru, Kenneth, Philpott, Dana J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Symposium section reviews: New frontiers in gastrointestinal physiology and pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117586/
https://ncbi.nlm.nih.gov/pubmed/29806140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275396
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