A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

Defining the full spectrum of human disease associated with a biomarker is necessary to advance the biomarker into clinical practice. We hypothesize that associating biomarker measurements with electronic health record (EHR) populations based on shared genetic architectures would establish the clini...

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Argitaratua izan da:Nat Commun
Egile Nagusiak: Mosley, Jonathan D., Feng, QiPing, Wells, Quinn S., Van Driest, Sara L., Shaffer, Christian M., Edwards, Todd L., Bastarache, Lisa, Wei, Wei-Qi, Davis, Lea K., McCarty, Catherine A., Thompson, Will, Chute, Christopher G., Jarvik, Gail P., Gordon, Adam S., Palmer, Melody R., Crosslin, David R., Larson, Eric B., Carrell, David S., Kullo, Iftikhar J., Pacheco, Jennifer A., Peissig, Peggy L., Brilliant, Murray H., Linneman, James G., Namjou, Bahram, Williams, Marc S., Ritchie, Marylyn D., Borthwick, Kenneth M., Verma, Shefali S., Karnes, Jason H., Weiss, Scott T., Wang, Thomas J., Stein, C. Michael, Denny, Josh C., Roden, Dan M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117367/
https://ncbi.nlm.nih.gov/pubmed/30166544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05624-4
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