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Class I and II Histone Deacetylase Inhibitors Differentially Regulate Thermogenic Gene Expression in Brown Adipocytes

Class I histone deacetylase inhibitors (HDACis) enhance whole body energy expenditure and attenuate high fat diet-induced insulin resistance. However, it is not clear whether this is exerted directly through activating brown fat thermogenesis. Here, we find that pan-HDACi TSA exerts paradoxical effe...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Rajan, Anubama, Shi, Hang, Xue, Bingzhong
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117331/
https://ncbi.nlm.nih.gov/pubmed/30166563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31560-w
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