The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation

Brown adipocytes function to dissipate energy as heat through adaptive thermogenesis. Understanding the molecular mechanisms underlying the brown fat thermogenic program may provide insights for the development of therapeutic approaches in the treatment of obesity. Most studies investigating the mec...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Zha, Lin, Li, Fenfen, Wu, Rui, Artinian, Liana, Rehder, Vincent, Yu, Liqing, Liang, Houjie, Xue, Bingzhong, Shi, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599018/
https://ncbi.nlm.nih.gov/pubmed/26306033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662650
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