The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation

Brown adipocytes function to dissipate energy as heat through adaptive thermogenesis. Understanding the molecular mechanisms underlying the brown fat thermogenic program may provide insights for the development of therapeutic approaches in the treatment of obesity. Most studies investigating the mec...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zha, Lin, Li, Fenfen, Wu, Rui, Artinian, Liana, Rehder, Vincent, Yu, Liqing, Liang, Houjie, Xue, Bingzhong, Shi, Hang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4599018/
https://ncbi.nlm.nih.gov/pubmed/26306033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.662650
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