Exosomes From Human Cardiac Progenitor Cells for Therapeutic Applications: Development of a GMP-Grade Manufacturing Method

Exosomes, nanosized membrane vesicles secreted by cardiac progenitor cells (Exo-CPC), inhibit cardiomyocyte apoptosis under stress conditions, promote angiogenesis in vitro, and prevent the early decline in cardiac function after myocardial infarction in vivo in preclinical rat models. The recogniti...

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Bibliografske podrobnosti
izdano v:Front Physiol
Main Authors: Andriolo, Gabriella, Provasi, Elena, Lo Cicero, Viviana, Brambilla, Andrea, Soncin, Sabrina, Torre, Tiziano, Milano, Giuseppina, Biemmi, Vanessa, Vassalli, Giuseppe, Turchetto, Lucia, Barile, Lucio, Radrizzani, Marina
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117231/
https://ncbi.nlm.nih.gov/pubmed/30197601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.01169
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