NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson’s disease

BACKGROUND: In Parkinson’s disease (PD), loss of striatal dopaminergic (DA) terminals and degeneration of DA neurons in the substantia nigra (SN) are associated with inflammation. Nucleotide-binding oligomerization domain-containing protein (NOD)2, one of the first discovered NOD-like receptors, pla...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Cheng, Li, Chen, Lin, Wei, Xinbing, Wang, Yimeng, Ren, Zhiping, Zeng, Shenglan, Zhang, Xiumei, Wen, Haitao, Gao, Chengjiang, Liu, Huiqing
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116377/
https://ncbi.nlm.nih.gov/pubmed/30157869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1289-z
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