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Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats

Orellanine is a nephrotoxin found in mushrooms of the Cortinarius family. Accidental intake of this substance may cause renal failure. Orellanine is specific for proximal tubular cells and could, therefore, potentially be used as treatment for metastatic renal cancer, which originates from these cel...

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Détails bibliographiques
Publié dans:Toxins (Basel)
Auteurs principaux: Najar, Deman, Haraldsson, Börje, Thorsell, Annika, Sihlbom, Carina, Nyström, Jenny, Ebefors, Kerstin
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6116018/
https://ncbi.nlm.nih.gov/pubmed/30126099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10080333
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