Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy

IgA nephropathy (IgAN), the most common GN worldwide, is characterized by circulating galactose-deficient IgA (gd-IgA) that forms immune complexes. The immune complexes are deposited in the glomerular mesangium, leading to inflammation and loss of renal function, but the complete pathophysiology of...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Liu, Peidi, Lassén, Emelie, Nair, Viji, Berthier, Celine C., Suguro, Miyuki, Sihlbom, Carina, Kretzler, Matthias, Betsholtz, Christer, Haraldsson, Börje, Ju, Wenjun, Ebefors, Kerstin, Nyström, Jenny
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2017
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5619958/
https://ncbi.nlm.nih.gov/pubmed/28646076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016101103
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