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The Methylation Status of the Epigenome: Its Emerging Role in the Regulation of Tumor Angiogenesis and Tumor Growth, and Potential for Drug Targeting

Approximately 50 years ago, Judah Folkman raised the concept of inhibiting tumor angiogenesis for treating solid tumors. The development of anti-angiogenic drugs would decrease or even arrest tumor growth by restricting the delivery of oxygen and nutrient supplies, while at the same time display min...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pirola, Luciano, Ciesielski, Oskar, Balcerczyk, Aneta
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115976/
https://ncbi.nlm.nih.gov/pubmed/30103412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10080268
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