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The Methylation Status of the Epigenome: Its Emerging Role in the Regulation of Tumor Angiogenesis and Tumor Growth, and Potential for Drug Targeting

Approximately 50 years ago, Judah Folkman raised the concept of inhibiting tumor angiogenesis for treating solid tumors. The development of anti-angiogenic drugs would decrease or even arrest tumor growth by restricting the delivery of oxygen and nutrient supplies, while at the same time display min...

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Publicat a:Cancers (Basel)
Autors principals: Pirola, Luciano, Ciesielski, Oskar, Balcerczyk, Aneta
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115976/
https://ncbi.nlm.nih.gov/pubmed/30103412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10080268
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