Removal of the N-Glycosylation Sequon at Position N116 Located in p27 of the Respiratory Syncytial Virus Fusion Protein Elicits Enhanced Antibody Responses after DNA Immunization

Prevention of severe lower respiratory tract infections in infants caused by the human respiratory syncytial virus (hRSV) remains a major public health priority. Currently, the major focus of vaccine development relies on the RSV fusion (F) protein since it is the main target protein for neutralizin...

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Bibliographische Detailangaben
Veröffentlicht in:Viruses
Hauptverfasser: Leemans, Annelies, Boeren, Marlies, Van der Gucht, Winke, Pintelon, Isabel, Roose, Kenny, Schepens, Bert, Saelens, Xavier, Bailey, Dalan, Martinet, Wim, Caljon, Guy, Maes, Louis, Cos, Paul, Delputte, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115940/
https://ncbi.nlm.nih.gov/pubmed/30110893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10080426
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