Evaluating the Impact of N-Glycan Sequon Removal in the p27 Peptide on RSV F Protein Immunogenicity and Functionality

Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in young children, elderly and immunocompromised patients worldwide. The RSV fusion (F) protein, which has 5–6 N-glycosylation sites depending on the strain, is a major target for vaccine development....

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Autores principales:	Lotte Jacobs, Annelies Leemans, Kim Stobbelaar, Axelle Fransen, Paul Cos, Peter Delputte
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-11-01
Colección:	Viruses
Materias:	RSV fusion protein p27 peptide N-glycosylation DNA immunization
Acceso en línea:	https://www.mdpi.com/1999-4915/16/12/1848
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