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Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse overexpressing galanin in neurons under the platelet-derived growth factor B promoter. RIA and HPLC an...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, Hilke, Susanne, Theodorsson, Elvar, Kahl, Ulrika, Bartfai, Tamas, Lindvall, Olle, Hökfelt, Tomas
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11698649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231496298
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