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Suppressed kindling epileptogenesis in mice with ectopic overexpression of galanin

The neuropeptide galanin has been shown to suppress epileptic seizures. In cortical and hippocampal areas, galanin is normally mainly expressed in noradrenergic afferents. We have generated a mouse overexpressing galanin in neurons under the platelet-derived growth factor B promoter. RIA and HPLC an...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kokaia, Merab, Holmberg, Kristina, Nanobashvili, Avtandil, Xu, Zhi-Qing D., Kokaia, Zaal, Lendahl, Urban, Hilke, Susanne, Theodorsson, Elvar, Kahl, Ulrika, Bartfai, Tamas, Lindvall, Olle, Hökfelt, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11698649/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231496298
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