Rapid and simple detection of Tamiflu-resistant influenza virus: Development of oseltamivir derivative-based lateral flow biosensor for point-of-care (POC) diagnostics

We have developed a novel oseltamivir derivative (oseltamivir hexylthiol; OHT) that exhibits a higher binding affinity for Tamiflu-resistant virus (Tamiflu resistance) than for the wild-type virus (Tamiflu-susceptible virus; WT) as an antibody. First, OHT-modified gold nanoparticles (OHT-GNPs) are u...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Hwang, Seul Gee, Ha, Kab, Guk, Kyeonghye, Lee, Do Kyung, Eom, Gayoung, Song, Sinae, Kang, Taejoon, Park, Hwangseo, Jung, Juyeon, Lim, Eun-Kyung
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6115449/
https://ncbi.nlm.nih.gov/pubmed/30158601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31311-x
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