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Development of A Concise Synthesis of (−)-Oseltamivir (Tamiflu®)
We report a full account of our work towards the development of an eight-step synthesis of anti-influenza drug (−)-oseltamivir (Tamiflu®) from commercially available starting material. The final synthetic route proceeds with an overall yield of 30 %. Key transformations include a novel palladium-cat...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3079541/ https://ncbi.nlm.nih.gov/pubmed/21365707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201003454 |
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