Abnormal regulation of BCR signalling by c-Cbl in chronic lymphocytic leukaemia

Abnormalities of molecules involved in signal transduction pathways are connected to Chronic Lymphocytic Leukemia (CLL) pathogenesis and a critical role has been already ascribed to B-Cell Receptor (BCR)-Lyn axis. E3 ubiquitin ligase c-Cbl, working together with adapter protein CIN85, controls the d...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Martini, Veronica, Frezzato, Federica, Severin, Filippo, Raggi, Flavia, Trimarco, Valentina, Martinello, Leonardo, Molfetta, Rosa, Visentin, Andrea, Facco, Monica, Semenzato, Gianpietro, Paolini, Rossella, Trentin, Livio
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6114956/
https://ncbi.nlm.nih.gov/pubmed/30181811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25951
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