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BAG3 regulates stability of IL-8 mRNA via interplay between HuR and miR-4312 in PDACs

Bcl-2 associated athanogene 3 (BAG3) is highly expressed in pancreatic ductal adenocarcinoma (PDAC), and its high expression appears to be a poor prognostic factor for patients with PDAC. In this study, we show that BAG3 knockdown significantly decreases migration and invasion of PDACs via reduction...

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Vydáno v:Cell Death Dis
Hlavní autoři: Li, Chao, Jiang, Jing-Yi, Wang, Jia-Mei, Sun, Jia, An, Ming-Xin, Li, Si, Yan, Jing, Wang, Hua-Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113235/
https://ncbi.nlm.nih.gov/pubmed/30154469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0874-5
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