IL‐22 sustains epithelial integrity in progressive kidney remodeling and fibrosis

IL‐22, a member of the IL‐10 cytokine family, accelerates tubule regeneration upon acute kidney injury, hence we speculated on a protective role also in chronic kidney disease. We quantified intrarenal IL‐22 expression after unilateral ureteral (UUO) in wild‐type mice and performed UUO in IL‐22 knoc...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Weidenbusch, Marc, Song, Shangqing, Iwakura, Takamasa, Shi, Chongxu, Rodler, Severin, Kobold, Sebastian, Mulay, Shrikant R., Honarpisheh, Mohsen M., Anders, Hans‐Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113136/
https://ncbi.nlm.nih.gov/pubmed/30156011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13817
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