AMP Kinase Promotes Glioblastoma Bioenergetics and Tumor Growth

Stress is integral to tumor evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activate the bioenergetic sensor AMP kinase (AMPK), and tumor cells hijack an AMPK-regulated stress response pathway conserved in normal cells, to survive....

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Chhipa, Rishi Raj, Fan, Qiang, Anderson, Jane, Muraleedharan, Ranjithmenon, Huang, Yan, Ciraolo, Georgianne, Chen, Xiaoting, Waclaw, Ronald, Chow, Lionel M., Khuchua, Zaza, Kofron, Matthew, Weirauch, Matthew T., Kendler, Ady, McPherson, Christopher, Ratner, Nancy, Nakano, Ichiro, Dasgupta, Nupur, Komurov, Kakajan, Dasgupta, Biplab
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113057/
https://ncbi.nlm.nih.gov/pubmed/29915361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0126-z
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