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AMP Kinase Promotes Glioblastoma Bioenergetics and Tumor Growth

Stress is integral to tumor evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activate the bioenergetic sensor AMP kinase (AMPK), and tumor cells hijack an AMPK-regulated stress response pathway conserved in normal cells, to survive....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Cell Biol
Päätekijät: Chhipa, Rishi Raj, Fan, Qiang, Anderson, Jane, Muraleedharan, Ranjithmenon, Huang, Yan, Ciraolo, Georgianne, Chen, Xiaoting, Waclaw, Ronald, Chow, Lionel M., Khuchua, Zaza, Kofron, Matthew, Weirauch, Matthew T., Kendler, Ady, McPherson, Christopher, Ratner, Nancy, Nakano, Ichiro, Dasgupta, Nupur, Komurov, Kakajan, Dasgupta, Biplab
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113057/
https://ncbi.nlm.nih.gov/pubmed/29915361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0126-z
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