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Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation
Rare variants, in particular renal salt handling genes, contribute to monogenic forms of hypertension and hypotension syndromes with electrolyte abnormalities. A study by Ji et al (2008) demonstrated this effect for rare loss-of-function coding variants in SLC12A3 (NCCT), SLC12A1 (NKCC2), and KCNJ1...
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| Publicado no: | Medicine (Baltimore) |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wolters Kluwer Health
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6113003/ https://ncbi.nlm.nih.gov/pubmed/30113482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000011865 |
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