Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival

The antimicrobial effect of nitric oxide (NO) is an essential part of innate immunity. The vigorous host response to the human gastric pathogen Helicobacter pylori fails to eradicate the organism, despite up-regulation of inducible NO synthase (iNOS) in the gastric mucosa. Here we report that wild-t...

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Bibliografiske detaljer
Main Authors: Gobert, Alain P., McGee, David J., Akhtar, Mahmood, Mendz, George L., Newton, Jamie C., Cheng, Yulan, Mobley, Harry L. T., Wilson, Keith T.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC61129/
https://ncbi.nlm.nih.gov/pubmed/11717441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241443798
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