Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca(2+)-dependent HIF-1α/ERRα circuit

Heme oxygenase-1 (HO-1) exerts beneficial effects, including angiogenesis and energy metabolism via the hypoxia-inducible factor-1α (HIF-1α) and peroxisome-proliferator-activating receptor-γ coactivator-1α (PGC-1α)/estrogen-related receptor α (ERRα) pathways, respectively, in astrocytes. However, ev...

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Publicado en:PLoS One
Main Authors: Choi, Yoon Kyung, Park, Joon Ha, Yun, Jung-A, Cha, Jong-Ho, Kim, Yonghee, Won, Moo-Ho, Kim, Kyu-Won, Ha, Kwon-Soo, Kwon, Young-Guen, Kim, Young-Myeong
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112640/
https://ncbi.nlm.nih.gov/pubmed/30153269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202039
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