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Heme oxygenase metabolites improve astrocytic mitochondrial function via a Ca(2+)-dependent HIF-1α/ERRα circuit
Heme oxygenase-1 (HO-1) exerts beneficial effects, including angiogenesis and energy metabolism via the hypoxia-inducible factor-1α (HIF-1α) and peroxisome-proliferator-activating receptor-γ coactivator-1α (PGC-1α)/estrogen-related receptor α (ERRα) pathways, respectively, in astrocytes. However, ev...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6112640/ https://ncbi.nlm.nih.gov/pubmed/30153269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202039 |
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