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A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice
Colitic lesions are much more severe in C3H/HeJBir (C3H) than C57BL/6J (B6) mice after 10 backcrosses of a disrupted interleukin-10 (Il10) gene. This study identified cytokine deficiency-induced colitis susceptibility (Cdcs) modifiers by using quantitative trait locus (QTL) analysis. A segregating F...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC61125/ https://ncbi.nlm.nih.gov/pubmed/11707574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241258698 |
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