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Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse

Evidence suggests that the specification of primordial germ cells (PGCs) in the mammalian embryo does not depend on maternal determinants. Rather, previous genetic analysis in the mouse has shown that bone morphogenetic protein 4 (Bmp4) is required for the formation of both PGCs and allantois. Bmp4...

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Detalhes bibliográficos
Main Authors: Fujiwara, Takeshi, Dunn, N. Ray, Hogan, Brigid L. M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC61111/
https://ncbi.nlm.nih.gov/pubmed/11707591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241508898
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