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Bone morphogenetic protein 4 in the extraembryonic mesoderm is required for allantois development and the localization and survival of primordial germ cells in the mouse

Evidence suggests that the specification of primordial germ cells (PGCs) in the mammalian embryo does not depend on maternal determinants. Rather, previous genetic analysis in the mouse has shown that bone morphogenetic protein 4 (Bmp4) is required for the formation of both PGCs and allantois. Bmp4...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Fujiwara, Takeshi, Dunn, N. Ray, Hogan, Brigid L. M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC61111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11707591/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.241508898
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