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Modeling the impact of drug interactions on therapeutic selectivity
Combination therapies that produce synergistic growth inhibition are widely sought after for the pharmacotherapy of many pathological conditions. Therapeutic selectivity, however, depends on the difference between potency on disease-causing cells and potency on non-target cell types that cause toxic...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6110842/ https://ncbi.nlm.nih.gov/pubmed/30150706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05954-3 |
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