S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease

Pro-inflammatory and amyloidogenic S100A9 protein is an important contributor to Alzheimer’s disease (AD) pathology. Traumatic brain injury (TBI) is viewed as a precursor state for AD. Here we have shown that S100A9-driven amyloid-neuroinflammatory cascade was initiated in TBI and may serve as a mec...

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Publicado en:Sci Rep
Main Authors: Wang, Chao, Iashchishyn, Igor A., Pansieri, Jonathan, Nyström, Sofie, Klementieva, Oxana, Kara, John, Horvath, Istvan, Moskalenko, Roman, Rofougaran, Reza, Gouras, Gunnar, Kovacs, Gabor G., Shankar, S. K., Morozova-Roche, Ludmilla A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110751/
https://ncbi.nlm.nih.gov/pubmed/30150640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31141-x
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