Co-aggregation of pro-inflammatory S100A9 with α-synuclein in Parkinson’s disease: ex vivo and in vitro studies

BACKGROUND: Chronic neuroinflammation is a hallmark of Parkinson’s disease (PD) pathophysiology, associated with increased levels of pro-inflammatory factors in PD brain tissues. The pro-inflammatory mediator and highly amyloidogenic protein S100A9 is involved in the amyloid-neuroinflammatory cascad...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Horvath, Istvan, Iashchishyn, Igor A., Moskalenko, Roman A., Wang, Chao, Wärmländer, Sebastian K. T. S., Wallin, Cecilia, Gräslund, Astrid, Kovacs, Gabor G., Morozova-Roche, Ludmilla A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987543/
https://ncbi.nlm.nih.gov/pubmed/29866153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1210-9
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