An engineered novel lentivector specifically transducing dendritic cells and eliciting robust HBV-specific CTL response by upregulating autophagy in T cells

Dendritic cells (DCs) play a predominant role in initiating cell immune responses. Here we generated a DC-targeting lentiviral vector (LVDC-UbHBcAg-LIGHT) and evaluated its capacity to elicit HBV-specific cytotoxic T lymphocyte (CTL) responses. DC-SIGN-mediated specific transduction using this const...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Ma, Siyuan, Chen, Xiaohua, Tan, Quanhui, Li, Dan, Dai, Shenglan, Wu, Shanshan, Yu, Yongsheng, Zang, Guoqing, Tang, Zhenghao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110602/
https://ncbi.nlm.nih.gov/pubmed/30019620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2018.1471312
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