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Contribution of Calpain and Caspases to Cell Death in Cultured Monkey RPE Cells

PURPOSE: AMD is the leading cause of human vision loss after 65 years of age. Several mechanisms have been proposed: (1) age-related failure of the choroidal vasculature leads to loss of RPE; (2) RPE dysfunctions due to accumulation of phagocytized, but unreleased A2E (N-retinylidene-N-retinylethano...

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Библиографические подробности
Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Nakajima, Emi, Hammond, Katherine B., Hirata, Masayuki, Shearer, Thomas R., Azuma, Mitsuyoshi
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6110128/
https://ncbi.nlm.nih.gov/pubmed/29053764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-22325
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