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Calpain, Not Caspase, Is the Causative Protease for Hypoxic Damage in Cultured Monkey Retinal Cells

PURPOSE. Cell death occurring in human retina during AMD, high IOP, and diabetic retinopathy could be caused by activation of calpain or caspase proteolytic enzymes. The purpose of the present study was to determine whether calpains and/or caspase-3 were involved in cell death during retinal hypoxia...

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Detalhes bibliográficos
Main Authors: Nakajima, Emi, Hammond, Katherine B., Rosales, Jennifer L., Shearer, Thomas R., Azuma, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3207712/
https://ncbi.nlm.nih.gov/pubmed/21757584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7497
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