Indoleamine 2,3-dioxygenase-dependent expansion of T-regulatory cells maintains mucosal healing in ulcerative colitis

BACKGROUND: Dendritic cell (DC)-derived indolamine 2,3-dioxygenase (IDO) degrades tryptophan to kynurenine, which promotes conversion of inflammatory T cells in immunosuppressive regulatory T cells (Tregs). We analyzed the significance of the IDO:Treg axis for inducing and maintaining mucosal healin...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Therap Adv Gastroenterol
Main Authors: Acovic, Aleksandar, Simovic Markovic, Bojana, Gazdic, Marina, Arsenijevic, Aleksandar, Jovicic, Nemanja, Gajovic, Nevena, Jovanovic, Marina, Zdravkovic, Natasa, Kanjevac, Tatjana, Harrell, C. Randall, Fellabaum, Crissy, Dolicanin, Zana, Djonov, Valentin, Arsenijevic, Nebojsa, Lukic, Miodrag L., Volarevic, Vladislav
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109841/
https://ncbi.nlm.nih.gov/pubmed/30159037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756284818793558
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados