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Action Potential Initiation, Propagation, and Cortical Invasion in the Hyperdirect Pathway during Subthalamic Deep Brain Stimulation

BACKGROUND: High frequency (~130 Hz) deep brain stimulation (DBS) of the subthalamic region is an established clinical therapy for the treatment of late stage Parkinson’s disease (PD). Direct modulation of the hyperdirect pathway, defined as cortical layer V pyramidal neurons that send an axon colla...

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Detalhes bibliográficos
Publicado no:Brain Stimul
Main Authors: Anderson, Ross W., Farokhniaee, AmirAli, Gunalan, Kabilar, Howell, Bryan, McIntyre, Cameron C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109410/
https://ncbi.nlm.nih.gov/pubmed/29779963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brs.2018.05.008
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